To survive and sustain businesses during such times of crisis becomes difficult for managers and entrepreneurs. This in turn amplifies the importance of designing new flexible and adaptive business models. This book addresses different business situations that occur during national and global crises, such as the COVID-19 pandemic. Specifically, it proposes new and inspiring business models for various industries such as service and retail industry using different statistical software like SPSS and AMOS. It discusses the various changing elements of businesses such as the application of artificial intelligence (AI) and machine learning and how to cope with these unexpected business elements to maintain sustainable development.